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Dr. Rebecca Lyczak

Research Interests

EDUCATION    

Ph.D., 1999 Cornell University, Weill Graduate School of Medical Sciences/Memorial Sloan-Kettering Institute,
New York, NY 
Thesis: Delta-Notch signaling in cell fate decisions: A role during skin appendage and cartilage
development in the chick embryo

B.S., 1994 College of New Jersey (formerly Trenton State College), Trenton, NJ
Double Major: Biology and Education


PROFESSIONAL  EXPERIENCE  

2002-present Assistant Professor, Department of Biology,
Ursinus College, Collegeville, PA
1999-2002 Postdoctoral Research Associate,
Institute of Molecular Biology, University of Oregon, Eugene, OR

 

COURSES TAUGHT

                                                    BIO213            Genetics
                                                    BIO213L            Genetics Lab
                                                    BIO346            Developmental Biology
                                                    BIO346L                   Developmental Biology Lab
                                                    BIO425W                       Molecular Genetics

 
AWARDS & FUNDING

2006-2007 Merck BPR&D Undergraduate Research Grant
2005-2008 NIH-AREA R1501 GM072523-01/G228MZ “Polarity and meiotic exit in the early C. elegans embryo”
2004, 2005 Merck-Summer Undergraduate Science
Research Fellowship
2002-present Internal Funding Sources (HHMI, Van Sant)
2003 Poster Prize,
14th International C. elegans Meeting,
Los Angeles, CA
2000-2002 Postdoctoral fellowship, American Cancer Society

 

PROFESSIONAL SOCIETIES

2005-present

Genetics Society of America

2001-present

Society for Developmental Biology

2000-present

American Society for Cell Biology

 

SELECTED PUBLICATION & PRESENTATIONS

*denotes undergraduate author

Lyczak, R., Zweier, L.*, Group, T.*, Murrow, M.A.*, Snyder, C.*, Klovitz, L.*, Beatty, A.*, Smith, K.*, Bowerman, B. (2006)
The puromycin-sensitive aminopeptidase PAM-1 is required for meiotic exit and anteroposterior polarity in the one-cell Caenorhabditis elegans embryo.  Development 133, 4281-4292.

Willis, J.H., Munro, E., Lyczak, R., and Bowerman, B. (2006)
Conditional dominant mutations in the C. elegans gene act-2 identify cytoplasmic and muscle roles for a redundant actin isoform.  Molecular Biology of the Cell 17, 1051-1064.

Encalada, S.E., Willis, J., Lyczak, R. and Bowerman, B. (2005)
A spindle checkpoint functions during mitosis in the early Caenorhabditis elegans embro.  Molecular Biology of the Cell 16, 1056-1070.

Beatty, A*, Mazor, A.*, Brewer, A.*, Smith, K.*, Murrow, M.*, Appleman, V.*, and Lyczak, R. (2004)
Analysis of meiotic exit and axis polarization in Caenorhabditis elegans.
Molecular Biology of the Cell (supplement) 15, 481. 
Phillips, J. B., Lyczak, R., Ellis, G., and Bowerman, B. (2004)  Roles for two partially redundant a-tubulins in early Caenorhabditis elegans embryos.
Cell Motility and the Cytoskeleton 58, 112-126. 
Ellis, G. C., Phillips, J. B., O’Rourke, S., Lyczak, R., and Bowerman, B. (2004)
Maternally expressed and partially redundant b-tubulins in Caenorhabditis elegans exhibit autoregulation.
J. Cell Science 117, 767-775.
Lyczak, R., Kirkegaard, S.*, and Bowerman, B. (2003)
The scu-1 gene is required for anterior-posterior axis specification and meiotic exit in the early Caenorhabditis elegans embryo.
Developmental Biology 259, 500. (abstract)
Lyczak, R., Gomes, J.-E., and Bowerman, B. (2002). Heads or Tails: Axis Formation and cell polarity in the early Caenorhabditis elegans embryo
Developmental Cell
Rappleye, C., Tagawa, A., Lyczak, R., Bowerman, B.,
and Aroian, R. V. (2002)
The anaphase-promoting complex and separin are required for embryonic anterior-posterior axis formation. Developemental Cell 2, 195-206.
Encalada, S. E., Martin, P. R., Phillips, J. B., Lyczak, R., Hamill, D. R., Swan, K. A., and Bowerman, B. (2000)
DNA replication defects delay cell division and disrupt cell polarity in early Caenorhabditis elegans embryos. Developmental Biology 228, 225-238.
Crowe, R., Zikherman, J., and Niswander, L..(1999) Delta-1 negatively regulates the transition  from prehypertrophic to hypertrophic chondrocytes during cartilage formation. Development 126, 987-998.

Crowe, R. and Niswander, L. (1998)Disruption of scale development by Delta-1 misexpression. Developmental Biology 95, 70-74.

Crowe, R., Henrique, D., Ish-Horowicz, D., and Niswander, L. (1998) A new role for Notch and Delta in cell fate decisions: patterning the feather array. Development. 125, 767-775.